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& Fragoulis, G
The primary concern for the FDA was the lack of large-scale, randomized controlled trials, which are the gold standard for new drug approval
Koves, T
Concerns regarding a link between GLP-1 and the more common papillary thyroid carcinoma (PTC) have also been raised as cells of this lineage do express GLP-R more than normal thyroid tissue 51 although evidence that the use of these drugs in humans causes increased cellular proliferation is not conclusive
It can also support weight loss alongside a healthy diet and exercise
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