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Effects of Semaglutide in Doxorubicin-Induced Cardiac Toxicity in Wistar Albino Rats [PMID: 38952352] Laboratory literature summary: Effects of Semaglutide in Doxorubicin-Induced Cardiac Toxicity in Wistar Albino Rats
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10.1111/dom.14765 43 KnopF
Investigators, semaglutide and cardiovascular outcomes in patients with type 2 diabetes
Yes, tirzepatide should be discontinued when pregnancy is recognized or before planned conception
Semaglutide downregulates the transcription factor PPARG, thereby reducing its inhibition of the downstream molecule ACSL1, leading to increased ACSL1 expression and promoting M1 polarization, ultimately enhancing the anti-tumor effects [95]
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