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To give this context, MT-II is being reviewed at the next PCAC meeting for potential inclusion in the 503A bulks list
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First, diabetes blunts weight loss by roughly 6 to 7 percentage points versus non-diabetic obesity at the same dose, because long-standing high glucose dampens the metabolic cascade the drug works through. Second, the 10-to-15 mg step keeps adding weight loss in every band
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The combination cagrilintide and semaglutide group had a time in range of 88.9% at 32 weeks compared with a 76.2% time in range with semaglutide and a 71.7% time in range with cagrilintide
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