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Hepatic vs Systemic IGF-1: A Research Framework IGF-1 in the body comes from two functionally distinct sources, and IGF-1 LR3 research is most useful when this distinction is kept in mind
They can bind to the protein, membrane lipids, nucleic acid, enzymes, and other small molecules
That review is the single most useful anchor for framing everything that follows: mild, dose-dependent, and under-studied long-term, not dangerous by default
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Direct transdifferentiation gives rise to the earliest new hair cells in regenerating avian auditory epithelium
Nat Rev Endocrinol (2012) 8(12):72842
This creates an outlet obstruction
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