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Preclinical studies in animal models have reported associations with metabolic and adipose-tissue endpoints

Accordingly, DPP-4 has been proposed to function as a locally acting adipokine with influence on insulin sensitivity

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DSIP-CBBBP Fusion Peptide BBB Delivery Research (2024) The 2024 Frontiers in Pharmacology study by Shao and colleagues investigated a DSIP-CBBBP (cell-penetrating peptide) fusion construct expressed in Pichia pastoris in a PCPA-induced insomnia mouse model