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The following hormones were assessed: total testosterone (TT), follicular stimulating hormone (FSH), prolactin, luteinizing hormone (LH), and estradiol

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Dosing began at 0.25 mg of each active drug and escalated every four weeks until the full 2.4 mg dose was reached by week 16

Theoretical determination of the Co-C bond energy dissociation in cobalamins

MNS-DOX and DNS-DOX were converted by MGST1 and GSTP1-1 via sulfonamide cleavage into the active parent drug (Fig

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