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PLATEAU captures subjects at treatment initiation, running 68 weeks to a primary endpoint of percent change in total body weight, with DXA-measured fat mass, lean mass, stair-climb performance, mobility, bone mineral density, and HbA1c as key secondaries

Supportive Weight Management : This program equips patients with effective strategies and tools to help maintain their weight with the support of our expert doctors and specialists

Resistance training and adequate protein intake can neutralize muscle loss, enhance physical function, and maintain lean body mass

doi:10.1172/JCI60016

Retatrutide activates three metabolic receptors (GLP-1, GIP, glucagon) versus one for semaglutide and two for tirzepatide

The modeled spectral range was from 0.2 to 4.2 ppm