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HF can lead to liver complications such as congestive hepatopathy and ischemic liver injury, primarily through hemodynamic changes, including hepatic congestion and hypoperfusion

Marine macroalgae polyphenols as potential neuroprotective antioxidants in neurodegenerative diseases

Kidney problems have been reported in some people, particularly with repeated or high-dose treatments

11 While a number of different non-medication options exist for treatment of OSA, including lifestyle modifications, breathing devices, oral appliances, and surgical procedures, tirzepatide was approved by the FDA for moderate to severe obstructive sleep apnea in late 2024

It is worth noting that fatigue may also be coincidental and unrelated to GLP-1 therapy, arising from underlying conditions such as anaemia, thyroid dysfunction, depression, or sleep disorders

Requires glucose and IGF-1 monitoring