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Phosphodiesterase-5 inhibitors such as sildenafil are generally safe to use alongside GLP-1 medications, though they are contraindicated with nitrates and should be used cautiously in certain cardiovascular conditions
An ongoing clinical trial (NCT06939088) is currently studying the effects of tirzepatide specifically on alcohol intake, with results expected in the coming years
Front Endocrinol (Lausanne) 2022;13:1043789
"While the ASA's guidelines prioritize patient safety, the lack of robust data made it important to objectively assess the impact of these drugs on gastric emptying," Dr
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