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The completion of a Phase I trial is a significant milestone, as its primary objective is to assess safety and tolerability in human subjects
includes warnings that parenteral thiamine may cause anaphylaxis and that the benzyl alcohol preservative is contraindicated in neonates due to risk of serious reactions)
(2024) observed a strong correlation between GLP-1RAs treatment with a 19% decreased likelihood of glaucoma onset, which was particularly notable in patients receiving the agonists for periods extending beyond 3 years
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Science 290: 15711574 Weissman JS, Kim PS (1993) Effcient catalysis of disulphide bond rearrangements by protein disulphide isomerase
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