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Regulatory and ethical issues include donor consent, screening, traceability, potency, comparability after manufacturing changes, long-term follow-up and clear distinction between controlled clinical trials and unproven commercial stem cell interventions

5ad) and NF-B (Fig

doi:10.1021/acs.jafc.5b02914

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Subsequently, 1717 articles were excluded because they did not meet the inclusion criteria

Moreover, indole-3-carboxaldehyde enhances anti-PD-1 efficacy in CRC by inhibiting CD4 Treg differentiation and modulating the IDO1-kynurenine-AhR axis to bolster CD8 T-cell function, enhances anti-PD-1 efficacy in CRC [45]