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Linjawi S, Lee B-W, Tabak et al (2018) A 32-week randomized comparison of stepwise insulin intensification of biphasic insulin aspart (BIAsp 30) versus basal-bolus therapy in insulin-nave patients with type 2 diabetes

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While fine for absolute immediate single-use application, it's not recommended for any storage

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Increased serine phosphorylation and decreased tyrosine phosphorylation of insulin receptors and IRS can terminate insulin action, resulting in post-binding defects in insulin signal transduction and leading to insulin dysfunction in women with PCOS [49, 50]

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Avoid taking two doses to make up for a missed dose

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