While both are used to support weight loss, theyre actually very different in how they work, how long theyre used, and who theyre best for
Heard et al
GLP-1 Dissolvable Melts by Peak Now offer a needle-free, quick-absorbing option for weight loss
Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (Mounjaro) and chronic weight management (Zepbound) in adults with BMI 30 kg/m, or 27 kg/m with at least one weight-related comorbidity
Common denial reasons include step therapy requirements, BMI criteria, or formulary exclusions
They also cause a delay in stomach emptying, which can help people feel full so they eat less, making the drugs effective for weight loss