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Failure of DNA repair induces apoptosis through p53 activation, mitochondrial pathway induction, and persistent DNA damage response (DDR) signaling 8-10

Cytoprotective mechanism of the novel gastric peptide BPC157 in gastrointestinal tract and cultured enteric neurons and glial cells

Ligand-independent actions of estrogen receptors (ERs) have also been described, particularly in the uterus, where ER can be activated by growth factor pathways (e.g., IGF-1), leading to receptor recruitment to chromatin in the absence of estrogen binding (Meyer et al., 2011

This precluded the ability to perform intra-class comparisons

All mice were also habituated to handling and saline injections for 3 days before recording

4,6 Conclusion In general, DPP-4 inhibitors are effective at promoting moderate lowering of A1C and are associated with few adverse events