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Retinoids This comparison matters because retinoids are the gold standard in topical anti-aging

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"Until further investigations are done on liver stores and humans where this process is broken we can only go on our symptoms and what works for each individual to relieve these symptoms and to heal as much as possible

But since supplements tend to contain other ingredients, its hard to prove the results were directly related to collagen supplementation, Harvard Health says

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(PubMed) Booth SL, Golly I, Sacheck JM, et al