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If the enzyme is missing or its activity is reduced because of a mutation in the FMO3 gene, trimethylamine is not broken down and instead builds up in the body
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Immunohistochemical results, MMNSST is considered (Fig
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The C-terminal portion of the peptide ligand first engages the ECD through an alpha-helical interaction, forming an initial complex that positions the ligand for subsequent insertion of its N-terminal residues into the transmembrane domain (TMD)
The tan becomes visible during this window for most skin types
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