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Source: The Effectiveness of Cobalamin (B12) Treatment for Autism Spectrum Disorder: A Systematic Review and Meta-Analysis (2021) Methyl B12 as a syrup showed promising improvements in individuals with autism, most likely because it improved oxidative status

After 28 days, both potency and sterility become questionable

For a 5 mg vial, 2 mL creates 2,500 mcg/mL, a popular ratio for easy dosing

Excessive methyl supplementation taking too much methylfolate or methyl-B12 for your needs COMT mutations slow breakdown of neurotransmitters, causing buildup when you add more methyls Histamine issues methylation can increase histamine in some people

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