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Comparisons With Other Diabetes Therapies Putting GLP1s in context with other antidiabetic agents offers additional insights: Thiazolidinediones (TZDs) are associated with increased fracture risk, especially in women SGLT2 inhibitors have raised concerns in some trials, particularly canagliflozin DPP-4 inhibitors appear largely neutral regarding skeletal effects Against this backdrop, GLP1s may have a neutral or possibly safer profile, though the data are not conclusive
However, in humans the data is contradictory
New England Journal of Medicine , 390(8), 712-724
Published online June 10, 2025
Storage Store at temperatures not exceeding 30C
doi: 10.1016/j.jbc.2024.108047 114 ZhangYMoerkensMRamaiahgariSde BontHPriceLMeermanJet al
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