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Additional research indicated that the proper function of STAT3 is critical for maintaining intestinal homeostasis, and constitutive activation of the STAT3 signaling pathway in epithelial cells reduces tight junction protein expression within endothelial cells, consequently enhancing vascular permeability and contributing to tissue damage and disease progression (Spalinger et al., 2021)

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Precautions References In a randomized, single-blind, placebo-controlled trial including 150 obese participants, individuals received either 16g per day of native inulin or maltodextrin (placebo) along with dietary advice focused on consuming either inulin-rich or inulin-poor vegetables

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Additionally, animal feed supplements account for 4.8% , driven by the expanding use of L-carnitine in livestock and pet nutrition for improved growth and energy metabolism