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By now, there are a few studies on the pharmacokinetics and bioavailability of intranasal lamotrigine in rats and mice, showing promising results with high brain-targeting efficacy [247, 248], but further research has to be done especially regarding efficacy
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Head Neck Pathol 9:481487 Silva LVO, Arruda JAA, Martelli SJ et al (2018) A multicenter study of biopsied oral and maxillofacial lesions in a brazilian pediatric population
When we talk about bioavailability, we are talking about the difference between a product that works and a product that is just a waste of money
