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3 Incubation Setup Test compound is incubated with the selected metabolic system (microsomes, S9, or hepatocytes) at 37C in the presence of NADPH and appropriate cofactors

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Lysosomal accumulation was observed in SMCR8 deficient macrophages from Smcr8 /mice , possibly because of increased ROS (Mcalpine et al., 2018)

Instead, the body breaks the collagen down into smaller pieces called peptides

Thymosin Beta 4s effects are not fully understood

Feb 2019;4(1):102-108