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CHAOS trial demonstrated that -tocopherol is able to reduce the incidence of myocardial infarction, however, failed to reduce the mortality in cardiovascular diseases (Stephens et al

However, the same authors found that the carrier N59.1 and N459.3 strains and the invasive strain MC58 did not affect the barrier function of the Calu3 ALI monolayer (Dave et al., 2023)

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doi:10.1056/NEJMoa1603827

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