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The study aims to enroll 350 participants across three treatment groups to determine whether combining mirikizumab with tirzepatide leads to both symptom reduction or resolution and at least 10% body weight loss compared to mirikizumab with placebo

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Through this agreement, we aim to build on our experience targeting incretin biology to evaluate HS-10535 and its potential to provide additional cardiometabolic benefits beyond weight reduction. Under the agreement, Hansoh Pharma has granted Merck an exclusive global license to develop, manufacture and commercialize HS-10535

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Glucagon Receptor Activity Retatrutide also activates glucagon receptors, making it distinct from many previous peptide candidates