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IM near the target tissue (e.g., near a knee joint) can be used for localized effect some practitioners prefer this for acute tendon injuries
John's Wort, and with drugs that impair metabolism of serotonin (in particular MAOIs, both those intended to treat psychiatric disorders and also others such as linezolid [see Contraindications (4), Warnings and Precautions (5.7) and Drug Interactions (7.1)]
Zhang L, Li C, Zhu Q, Li N, Zhou H
18 For type 1 diabetes, the Diabetes Complications and Control Trial showed that complications--including retinopathy, nephropathy and neuropathy--can be delayed or prevented with intensive insulin therapy
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