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Because there is a need for dosage adjustment based upon renal function, assessment of renal function is recommended prior to initiation of Januvia and periodically thereafter

Some patients may lose over 30 pounds in 3 months, but we worry about the caloric deficit, muscle loss, nutrient deficiencies, and health risks that come with rapid weight loss

However, weight-loss drugs are included in a small group of drugs that can be excluded from coverage 1 (though the statutory exception refers to agents used for weight loss, obesity drugs is used to refer to this group of medications in this analysis)