It is what you would expect when you remove something the body had adapted around
The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence
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PC-12 Adh cells, with neuronal properties and high glucocorticoid receptor levels, are ideal for studying stress-related neuronal responses 78,79
When we evaluated FcRn-mediated recycling in a cell-based assay, where the receptor is embedded in the membrane, the WT fusion was recycled 1.8-fold less efficiently than unfused WT albumin, which is in line with its shorter plasma half-life