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What the literature actually describes is better summarized as copper-dependent enzyme cofactor logistics: the complex participates in the movement of copper between ligands of differing affinity, and the downstream observations follow from where the copper ends up

In the search for this prophesised molecule, Dr Joel Habener and his team at Massachusetts General Hospital decided in the late 1970s to study glucagon, another hormone produced by the pancreas that has an opposite action to insulin and increases blood glucose levels

References Griffith OW: Mammalian sulfur amino acid metabolism: an overview

Electron transport, oxidative phosphorylation, and mitochondrial respiration were among the most upregulated processes

doi:10.3389/fendo.2021.721135 6

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