Night = faster results (skin repairs during sleep)
This is when acetaldehyde levels peak, inflammation reaches its crescendo, and dehydration hits maximum intensity
Those changes reversed after discontinuation, with skin tone returning to baseline within 6 months
Guillaume JC, Jouffroy L, Touraine R
doi:10.1016/j.fertnstert.2005.06.028 Lydic ML, McNurlan M, Bembo S, Mitchell L, Komaroff E, Gelato M
"The risk of developing these severe side effects is very small, but it is important that patients and healthcare professionals are aware and alert to the associated symptoms." In the UK, the most commonly used GLP-1 therapies are Novo Nordisk's semaglutide-based Ozempic for diabetes and Wegovy for obesity, as well as Eli Lilly's Mounjaro (tirzepatide), which are all given as weekly injections