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Such medications need to be taken on a regular basis, once a week
Tirzepatide-based evidence from the SURPASS (Researching Tirzepatide in Patients with Type 2 Diabetes for Glycemic Control and Weight Management) trials (SURPASS-1 NCT03954834 and SURPASS-5 NCT04039503) demonstrated dose-dependent, significant weight loss over 40 weeks compared with placebo, along with reductions in BMI and waist circumference [62, 63]
Dose-dependent hypoglycemia risk exists, particularly when combined with insulin or sulfonylureas
When appetite is reduced, people often eat less fiber and drink less water without realizing it
Appetite changes vary enormously
GLP-1s address the underlying insulin resistance that drives both the metabolic and reproductive symptoms
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