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SS-31 targets mitochondrial function directly

Its full chemical name is 5-amino-1-methylquinolinium

They use HPLC purity verification and mass spectrometry for identity confirmation

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The research rationale for a selective NNMT inhibitor is to interrupt exactly that diversion, so the cell keeps more of its NAD+ pool and can run its mitochondrial machinery again

Its confidence interval spans zero and is wider than the point estimate, so it was too small to detect the difference it observed uninformative rather than null