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Understanding these aspects is critical for health care providers, payers and patients looking to balance health outcomes, affordability, and innovation
For instance, Sarah, a 35-year-old woman, struggled to lose the last 15 pounds despite rigorous dieting and exercise
Importantly, such plasticity is tightly regulated by epigenetic remodeling, metabolic adaptation, stress-response programs, and microenvironmental cues, highlighting the dynamic and reversible nature of resistance
PMID 19303062
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Immunosuppressive treatment and high-dose systemic B12 supplementation were associated with increased B12 in the CSF and clinical improvement
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