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Available as both an injection and an oral pill, semaglutide functions by mimicking the GLP-1 hormone, reducing appetite and sustaining weight loss

GLP-1 helps the pancreas release insulin when blood sugar rises and reduces the amount of glucose released by the liver

This means that as long as your pen stays sealed and refrigerated properly, you can trust that the medication will maintain its intended clinical strength

No significant differences in secondary outcomes were observed post-weighting, and all results were consistent across multiple sensitivity analyses

Levine is employed by Pfizer Inc., was employed by Eli Lilly and Company during the completion of this work, and holds stock in Pfizer Inc

Testosterone effects across the GLP-1 class A 2025 systematic review and meta-analysis examining GLP-1 RA effects on testosterone found consistent increases in total testosterone across multiple agents and studies