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In the STEP-2 clinical trial, patients with type 3 diabetes lost 9.6% of body weight, compared to 3.4% with placebo
Lancet 392(10161):22992312
Emerging research suggests some patients using GLP-1 receptor agonists may have inadequate protein intake and occasional sarcopenia, which raises concern about lean mass loss during treatment
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[20] [21] Dehydration represents another plausible mechanism, especially in patients experiencing gastrointestinal side effects
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