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JAMA 2003
It's not an approved drug, so it cannot be sold commercially with medical claims
Contrary to our findings, a previous study in mice showed that acute caffeine administration increased survival in a model of seizure-induced death 31
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Pyruvate dehydrogenase E1 subunit alpha 1 (Pdha1) promotes the transformation of ESCs into two-cell-like embryonic cells through a mechanism whereby the nuclear import of Pdha1 facilitates the direct synthesis of acetyl-CoA in the nucleus, providing a reaction substrate for histone acetylation modification and promoting histone H3 acetylation(Li 2022)
Galen Med J
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