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But, we need more studies to know how well it works and the best dose

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The 12-week trial showing 2.6 kg fat loss versus 0.8 kg placebo was run at 1 mg/day

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It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)