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It is not available by prescription and cannot legally be marketed for human consumption

Every labeled indication specifies use in combination with a reduced-calorie diet and increased physical activity, and trial participants were instructed to maintain approximately a 500 kcal/day deficit

HEART DISEASE DEATHS LINKED TO OBESITY HAVE TRIPLED IN 20 YEARS, STUDY FOUND: INCREASING BURDEN' (Participants who had type 2 diabetes were excluded, a spokesperson for the study told Fox News Digital.) Among those taking 8 mg doses of retatrutide, the relative decrease in liver fat was almost 82% after 48 weeks