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Libiad, M., Yadav, P

This modulation appears selective, as AOD 9604 does not activate the growth hormone receptor or induce downstream IGF-1 signaling

Sci Rep 9:117

Consequently, chemical-space analysis is a vital tool for virtual screening and the discovery of shared bioactivity regions across different peptide families

Oral corticosteroids (prednisone) provide short-term anti-inflammatory benefit but have significant side effect profiles with repeated courses, including bone density loss, immune suppression, and metabolic disruption

In response, personalized treatment and drug rechallenge strategies have emerged as adaptive precision approaches to address resistance dynamics