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In 58.8% (10/17) of patients, NIRS data were improved and ammonia levels were decreased, whereas 23.5% (4/17) of patients showed improved NIRS data without decreasing serum ammonia levels at 8 weeks
However, maintaining a calorie-deficient diet is also one of the hardest parts of following a medical weight loss program, as patients are encouraged to continue exercising and will experience increased hunger and cravings
Two pathologists independently read the liver biopsies for each patient
The 2024-2025 RCT and cohort data represent the most rigorous current human evidence, but this is an active research area, and the picture will continue to develop
