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Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease

These defects typically manifest as severe metabolic disorders, such as cardiomyopathy, encephalopathy, and hypoglycemia

Chez l'tre humain, la statohpatite non alcoolique (SHNA) est associe un accroissement de la lipogense, source de malonyl-CoA (M-CoA), linhibiteur de lenzyme cl de la -oxydation mitochondriale des acides gras (OAGmit) : la carnitine-palmitoyltransfrase 1A (CPT1-A) [19]