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people who combine Metformin with a balanced diet and regular exercise
Patients pay month to month, which gives them flexibility to pause or cancel if the medication is not working or if they experience intolerable side effects
A post-hoc analysis of SURMOUNT-5 estimated a larger reduction in predicted 10-year cardiovascular risk with tirzepatide (23.7%) than semaglutide (13.6%), but these are modeled projections, not measured outcomes
What We Know Semaglutide currently holds the strongest cardiovascular evidence
Despite this, many doctors have prescribed this medication to non-diabetic individuals to help them lose weight and to help prevent them from gaining weight back
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