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Nrf2 has been associated with significant increases in superoxide dismutase (SOD)1 and SOD2, which are mediators of oxidative stress [43, 44]
& Giordano, S
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In the phase 2 trial, 41% to 63% of participants receiving cagrilintide (0.3 to 4.5 mg) experienced gastrointestinal adverse events, compared to 32% with placebo
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