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However, under conditions of iron overload, excess Fe 2+ in the LIP undergoes Fenton chemistry with H 2 O 2 , producing excessive ROS, promoting lipid peroxidation, and ultimately triggering ferroptosis (Zhao et al., 2025a)

Apoptosis is characterized by activation of caspase-3 and subsequent cleavage of PARP into 89- and 24-kDa fragments 18

Until then, Rybelsus may be preferable for people who dont want to inject themselves