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Anti-obesity and glucose-lowering pharmacotherapies predominantly exert their actions by inducing satiety (liraglutide, setmelanotide, lorcaserin, pramlintide, sibutramine) or by inducing malabsorption of nutrients (orlistat)

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This matters because visceral fat is the metabolically active fat that secretes inflammatory cytokines, drives insulin resistance, and deposits fat in the liver

That has started to change since Ousia relinquished its license, Bishop says

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