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Efficacy and safety of glucagon-like peptide-1 receptor agonists in the elderly versus non-elderly patients with type 2 diabetes mellitus: insights from a systematic review
Serious adverse events are rare when tirzepatide is prescribed and managed appropriately, with most patients experiencing improved tolerability as weeks progress and their body stabilizes on a therapeutic dose
Some patients taking GLP-1 drugs have reported that cravings tied to food, alcohol or other compulsive behaviors became quieter after beginning treatment
The consequence is the formation of a cataract [10]
Rather than reducing the total weekly amount, which would diminish therapeutic benefit, the provider splits the existing dose into two injections
This has the potential to modulate downstream signalling by directing the ligand towards GLP-1Rs situated in sub-microscopic membrane domains variably enriched with signalling effectors on the cytoplasmic side (Villar et al ., 2016)
