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However, challenges persist, and further research is necessary to address unmet needs in early detection and screening, develop more effective and personalized therapeutic strategies, and further elucidate the molecular underpinnings of EC

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Notably, liraglutide was shown to restore the concentrations of bile acids, glycogen metabolism by-products, and pentoses, thus facilitating glycogen utilization turnover and nucleic acid formation [25]

Conclusions Together, this review highlights peripheral inflammation and misfolded alpha-synuclein as pivotal contributors to neuroinflammatory mechanisms in Parkinson disease, emphasizing monocyte-related pathways as promising targets for disease monitoring and intervention

Best JH, Hoogwerf BJ, Herman WH, Pelletier EM, Smith DB, Wenten M, et al