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Contrave, on the other hand, is designed for long-term use and tends to deliver more consistent results over time
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GLP-1 medications carry important warnings and contraindications, including a boxed warning for thyroid C-cell tumors in rodents (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2)
However, patients with severe mental illness (SMI) frequently demonstrate decreased motivation and an inability to adapt their diet and activity patterns [46, 47], which limits the effectiveness of lifestyle interventions [12]
Increase dietary protein to 0.7-1 gram per pound of body weight
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