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26,27 Suggestive evidence of hemoglobin A1c-lowering being the cause of the reported worsening with GLP-1/GIP agonists can be derived by comparing the results of two recent retrospective cohort studies assessing retinopathy outcomes between subjects treated with GLP-1/GIP agonists and sodium-glucose cotransporter-2 (SGLT2) inhibitors
Abbreviations AKI: Acute Kidney Injury BMI: Body Mass Index VAS: Visual Analog Scale SD: Standard Deviation IQR: Interquartile range CoA: Coenzyme A NF-B: Nuclear factor-kappa B IGF-1: Insulin-like Growth Factor 1 MAFLD: Metabolic Dysfunction-Associated Fatty Liver Disease References Konikoff F, Theodor E
The long-term outlook for patients affected by drug-induced NAION varies
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Maybe GLP-1s have done what no menu ever could: Theyre convincing insatiable Americans that less is more
Detection of TGR5, CBS, and CSE in STC-1 cells by RT-PCR STC-1 cells were treated with the RNAqueous reagent (Ambion, Austin, TX) for total RNA extraction
