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high-volume resistance training on the BDNF response to exercise
Marketed under the brand names Mounjaro (for diabetes) and Zepbound (for weight management in adults with BMI 30 kg/m or 27 kg/m with at least one weight-related comorbidity), tirzepatide represents the first dual incretin receptor agonist available in clinical practice
These injections work by breaking down fat cells, allowing the body to naturally eliminate them
Phase 2: Refinement (weeks 5 through 12) As you escalate through 5 mg and 7.5 mg, your side effect profile becomes clearer
Individuals with obesity should be counselled to accumulate at least 150 minutes a week of moderate aerobic exercise, such as walking, and to engage in resistance training to preserve lean mass
NICE recommends sleep hygiene measures and Cognitive Behavioural Therapy for Insomnia (CBT-I) as first-line treatments
