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Ngha l th phm c ch ra l hng rc v thi quen dng sai, khng phi bn thn hot cht glutathione trong mt sn phm t chun

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Intl Rev Cytol 1978;54:109-157

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This tissue distribution is pharmacologically relevant because GLP-1 receptors are expressed not only in the pancreatic islets (where they mediate insulinotropic effects) but also in the gastrointestinal tract (where they slow gastric emptying), the hypothalamus and brainstem (where they mediate appetite suppression), the cardiovascular system (where they may confer cardioprotective effects), and the kidneys (where they promote natriuresis)

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Many patients who have undergone cyclophosphamide treatment present with severe hemorrhagic cystitis

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The authors attributed the increased risk to activation of cytochrome P450 2E1 by alcohol and depletion of glutathione stores by starvation or alcohol abuse

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