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Bad sleep can actually increase insulin resistance and lower GLP-1 levels, increasing cravings, weight gain, and blood sugar levels

Injectable GLP-1s such as Wegovy have also demonstrated cardiovascular risk reduction in high-risk patients, an advantage not yet confirmed for the upcoming oral versions

This leads to the accumulation of misfolded or aggregated proteins, the activation of endoplasmic reticulum stress and unfolded protein response, and further aggravation of heat-induced cellular injury (Hetz et al., 2020

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We ascertained ischemic stroke-related hospitalization by primary diagnosis in inpatient records (see full list of ICD codes in eTable 2)

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